Angiopoietin 2 Antikörper (AA 19-485)
Kurzübersicht für Angiopoietin 2 Antikörper (AA 19-485) (ABIN7144092)
Target
Alle Angiopoietin 2 (ANGPT2) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 19-485
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Kreuzreaktivität
- Human, Maus, Ratte
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Aufreinigung
- >95%, Protein G purified
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Immunogen
- Recombinant Human Angiopoietin-2 protein (19-485AA)
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Isotyp
- IgG
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Applikationshinweise
- Recommended dilution: WB:1:500-1:5000, IHC:1:500-1:1000,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Angiopoietin 2 (ANGPT2)
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Andere Bezeichnung
- ANGPT2
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Hintergrund
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Background: Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal.
Aliases: AGPT 2 antibody, Agpt2 antibody, ANG 2 antibody, ANG-2 antibody, ANG2 antibody, Angiopoietin 2a antibody, Angiopoietin 2B antibody, Angiopoietin-2 antibody, Angiopoietin2 antibody, ANGP2_HUMAN antibody, ANGPT 2 antibody, Angpt2 antibody, Tie2 ligand antibody
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UniProt
- O15123
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Pathways
- RTK Signalweg
Target
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