AIMP1 Antikörper (AA 25-180)

Produktnummer ABIN7143995

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch AIMP1 in WB, ELISA, IHC und IF. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für AIMP1 Antikörper (AA 25-180) (ABIN7143995)

Target: AIMP1 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AIMP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-AIMP1 Antikörper

Bindungsspezifität: AA 25-180

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 protein (25-180AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu AIMP1

Target: AIMP1 (Aminoacyl tRNA Synthetase Complex-Interacting Multifunctional Protein 1 (AIMP1))

Andere Bezeichnung: AIMP1

Hintergrund:

Background: Non-catalytic component of the multisynthase complex. Stimulates the catalytic activity of cytoplasmic arginyl-tRNA synthase. Binds tRNA. Possesses inflammatory cytokine activity. Negatively regulates TGF-beta signaling through stabilization of SMURF2 by binding to SMURF2 and inhibiting its SMAD7-mediated degradation. Involved in glucose homeostasis through induction of glucagon secretion at low glucose levels. Promotes dermal fibroblast proliferation and wound repair. Regulates KDELR1-mediated retention of HSP90B1/gp96 in the endoplasmic reticulum. Plays a role in angiogenesis by inducing endothelial cell migration at low concentrations and endothelian cell apoptosis at high concentrations. Induces maturation of dendritic cells and monocyte cell adhesion. Modulates endothelial cell responses by degrading HIF-1A through interaction with PSMA7.

Aliases: AIMP 1 antibody, Aimp1 antibody, AIMP1/p43 antibody, AIMP1_HUMAN antibody, Aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 antibody, ARS interacting multifunctional protein 1 antibody, EMAP 2 antibody, EMAP-2 antibody, EMAP-II antibody, EMAP2 antibody, EMAPII antibody, Endothelial monocyte activating polypeptide 2 antibody, Endothelial monocyte activating polypeptide antibody, Endothelial monocyte-activating polypeptide 2 antibody, Endothelial monocyte-activating polypeptide II antibody, HLD3 antibody, Multisynthase complex auxiliary component p43 antibody, Multisynthetase complex auxiliary component p43 antibody, OTTHUMP00000219673 antibody, p43 antibody, Scye 1 antibody, Scye1 antibody, Scye1, formerly antibody, Small inducible cytokine subfamily E member 1 antibody, Small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating) antibody, Small inducible cytokine subfamily E, member 1, formerly antibody

UniProt: Q12904