Chromosome 6 Open Reading Frame 134 (C6orf134) (AA 194-238) Antikörper (Biotin)

Produktnummer ABIN7143949

Dieses Anti--Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von in ELISA. Geeignet für Human.

Kurzübersicht für Chromosome 6 Open Reading Frame 134 (C6orf134) (AA 194-238) Antikörper (Biotin) (ABIN7143949)

Target: Chromosome 6 Open Reading Frame 134 (C6orf134)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Biotin

Applikation: ELISA

Produktdetails

Bindungsspezifität: AA 194-238

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Alpha-tubulin N-acetyltransferase 1 protein (194-238AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Antigendetails

Target: Chromosome 6 Open Reading Frame 134 (C6orf134)

Andere Bezeichnung: ATAT1

Hintergrund:

Background: Specifically acetylates \'Lys-40\' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics, this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released. Required for normal sperm flagellar function. Promotes directional cell locomotion and chemotaxis, through AP2A2-dependent acetylation of alpha-tubulin at clathrin-coated pits that are concentrated at the leading edge of migrating cells. May facilitate primary cilium assembly.

Aliases: Acetyltransferase mec 17 homolog antibody, Acetyltransferase mec-17 homolog antibody, Alpha TAT antibody, Alpha tubulin acetyltransferase 1 antibody, Alpha tubulin N acetyltransferase antibody, Alpha-TAT antibody, Alpha-tubulin N-acetyltransferase antibody, ATAT_HUMAN antibody, ATAT1 antibody, Chromosome 6 open reading frame 134 antibody, Hypothetical protein LOC79969 antibody, MEC17 antibody, Nbla00487 antibody, TAT antibody

UniProt: Q5SQI0