Chromosome 6 Open Reading Frame 134 (C6orf134) (AA 194-238) Antikörper

Produktnummer ABIN7143948

Produktdetails

Target: Chromosome 6 Open Reading Frame 134 (C6orf134)

Bindungsspezifität: AA 194-238

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Alpha-tubulin N-acetyltransferase 1 protein (194-238AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:200-1:500,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Antigendetails

Target: Chromosome 6 Open Reading Frame 134 (C6orf134)

Andere Bezeichnung: ATAT1 (C6orf134 Produkte)

Synonyme: C6orf134 antikoerper, MEC17 antikoerper, Nbla00487 antikoerper, TAT antikoerper, mec17 antikoerper, wu:fj19c03 antikoerper, zgc:65893 antikoerper, zgc:77443 antikoerper, Alpha-TAT antikoerper, c6orf134 antikoerper, C23H6orf134 antikoerper, 0610011P08Rik antikoerper, 2610008K08Rik antikoerper, 2610110G12Rik antikoerper, 3110080J08Rik antikoerper, Mec17 antikoerper, RGD1303066 antikoerper, C7H6ORF134 antikoerper, C4H6orf134 antikoerper, alpha tubulin acetyltransferase 1 antikoerper, alpha tubulin acetyltransferase 1 S homeolog antikoerper, ATAT1 antikoerper, atat1 antikoerper, atat1.S antikoerper, Atat1 antikoerper

Hintergrund:

Background: Specifically acetylates \'Lys-40\' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics, this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dynamically unstable microtubules before the enzyme is released. Required for normal sperm flagellar function. Promotes directional cell locomotion and chemotaxis, through AP2A2-dependent acetylation of alpha-tubulin at clathrin-coated pits that are concentrated at the leading edge of migrating cells. May facilitate primary cilium assembly.

Aliases: Acetyltransferase mec 17 homolog antibody, Acetyltransferase mec-17 homolog antibody, Alpha TAT antibody, Alpha tubulin acetyltransferase 1 antibody, Alpha tubulin N acetyltransferase antibody, Alpha-TAT antibody, Alpha-tubulin N-acetyltransferase antibody, ATAT_HUMAN antibody, ATAT1 antibody, Chromosome 6 open reading frame 134 antibody, Hypothetical protein LOC79969 antibody, MEC17 antibody, Nbla00487 antibody, TAT antibody

UniProt: Q5SQI0