AFF4 Antikörper (AA 77-334)

Produktnummer ABIN7143566

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch AFF4 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für AFF4 Antikörper (AA 77-334) (ABIN7143566)

Target: AFF4 (AF4/FMR2 Family, Member 4 (AFF4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AFF4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-AFF4 Antikörper

Bindungsspezifität: AA 77-334

Kreuzreaktivität: Human, Maus

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human AF4/FMR2 family member 4 protein (77-334AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:2000-1:5000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu AFF4

Target: AFF4 (AF4/FMR2 Family, Member 4 (AFF4))

Andere Bezeichnung: AFF4

Hintergrund:

Background: Key component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by Key component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. In the SEC complex, AFF4 acts as a central scaffold that recruits other factors through direct interactions with ELL proteins (ELL, ELL2 or ELL3) and the P-TEFb complex. In case of infection by HIV-1 virus, the SEC complex is recruited by the viral Tat protein to stimulate viral gene expression.

Aliases: AFF4 antibody, AF5Q31 antibody, MCEF antibody, HSPC092 antibody, AF4/FMR2 family member 4 antibody, ALL1-fused gene from chromosome 5q31 protein antibody, Protein AF-5q31 antibody, Major CDK9 elongation factor-associated protein antibody

UniProt: Q9UHB7