ARFGAP1 Antikörper (AA 1-220)

Produktnummer ABIN7143460

Dieses Anti-ARFGAP1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ARFGAP1 in WB, ELISA und IHC. Geeignet für Human.

Kurzübersicht für ARFGAP1 Antikörper (AA 1-220) (ABIN7143460)

Target: ARFGAP1 (ADP-Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARFGAP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-ARFGAP1 Antikörper

Bindungsspezifität: AA 1-220

Kreuzreaktivität: Human, Maus

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human ADP-ribosylation factor GTPase-activating protein 1 protein (1-220AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu ARFGAP1

Target: ARFGAP1 (ADP-Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1))

Andere Bezeichnung: ARFGAP1

Hintergrund:

Background: GTPase-activating protein (GAP) for the ADP ribosylation factor 1 (ARF1). Involved in membrane trafficking and /or vesicle transport. Promotes hydrolysis of the ARF1-bound GTP and thus, is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles, a prerequisite for vesicle\\\'s fusion with target compartment. Probably regulates ARF1-mediated transport via its interaction with the KDELR proteins and TMED2. Overexpression induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, as when ARF1 is deactivated. Its activity is stimulated by phosphoinosides and inhibited by phosphatidylcholine .

Aliases: ADP ribosylation factor 1 GTPase activating protein antibody, ADP ribosylation factor GTPase activating protein 1 antibody, ADP-ribosylation factor 1 GTPase-activating protein antibody, ADP-ribosylation factor GTPase-activating protein 1 antibody, ARF GAP 1 antibody, ARF1 directed GTPase activating protein antibody, ARF1 GAP antibody, ARF1-directed GTPase-activating protein antibody, ARF1GAP antibody, ARFG1_HUMAN antibody, Arfgap1 antibody, GAP protein antibody, HRIHFB2281 antibody

UniProt: Q8N6T3

Pathways: p53 Signalweg, ER-Nucleus Signaling, Unfolded Protein Response