Serotonin Receptor 1A Antikörper (AA 230-334)

Produktnummer ABIN7142614

Dieser Anti-Serotonin Receptor 1A Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von Serotonin Receptor 1A in ELISA, IHC und IF. Geeignet für Human.

Kurzübersicht für Serotonin Receptor 1A Antikörper (AA 230-334) (ABIN7142614)

Target: Serotonin Receptor 1A (HTR1A)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Serotonin Receptor 1A Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-Serotonin Receptor 1A Antikörper

Bindungsspezifität: AA 230-334

Verwendungszweck: HTR1A Antibody

Aufreinigung: Protein G purified

Reinheit: >95 %

Immunogen: Recombinant Human 5-hydroxytryptamine receptor 1A protein (230-334AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu Serotonin Receptor 1A

Target: Serotonin Receptor 1A (HTR1A)

Andere Bezeichnung: HTR1A

Hintergrund:

Background: G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling inhibits adenylate cyclase activity and activates a phosphatidylinositol-calcium second messenger system that regulates the release of Ca(2+) ions from intracellular stores. Plays a role in the regulation of 5-hydroxytryptamine release and in the regulation of dopamine and 5-hydroxytryptamine metabolism. Plays a role in the regulation of dopamine and 5-hydroxytryptamine levels in the brain, and thereby affects neural activity, mood and behavior. Plays a role in the response to anxiogenic stimuli.

Aliases: 5 HT 1A antibody, 5 HT receptor 1A antibody, 5 HT1A antibody, 5 HT1A receptor antibody, 5 hydroxytryptamine (serotonin) receptor 1A antibody, 5 hydroxytryptamine (serotonin) receptor 1A G protein coupled antibody, 5 hydroxytryptamine receptor 1A antibody, 5-HT-1A antibody, 5-HT1A antibody, 5-hydroxytryptamine receptor 1A antibody, 5HT 1A antibody, 5HT 1A receptor antibody, 5HT receptor 1A antibody, 5HT1a antibody, 5HT1A_HUMAN antibody, ADRB2RL1 antibody, ADRBRL1 antibody, G 21 antibody, G protein coupled receptor antibody, G-21 antibody, Gpcr 18 antibody, Gpcr18 antibody, Guanine nucleotide binding regulatory protein-coupled receptor antibody, Htr1a antibody, PFMCD antibody, Serotonin 1A receptor antibody, Serotonin 5HT1A receptor antibody, Serotonin receptor 1A antibody

UniProt: P08908

Pathways: JAK-STAT Signalweg, Synaptic Membrane, Feeding Behaviour