WDR77 Antikörper

Produktnummer ABIN7140359

Dieses Maus Monoklonal-Antikörper erkennt spezifisch WDR77 in WB, ELISA und ICC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für WDR77 Antikörper (ABIN7140359)

Target: WDR77 (WD Repeat Domain 77 (WDR77))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser WDR77 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Produktdetails anti-WDR77 Antikörper

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Affinity purified

Immunogen: Purified recombinant human WDR77 protein fragments expressed in E.coli.

Isotyp: IgG1, IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Recommended dilution:WB:1:500-1:5000,ICC:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified mouse monoclonal in PBS( pH 7.4) containing with 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu WDR77

Target: WDR77 (WD Repeat Domain 77 (WDR77))

Andere Bezeichnung: WDR77

Hintergrund:

Background: Non-catalytic component of the 20S PRMT5-containing methyltransferase complex,which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins and histones.This modification targets Sm proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein core particles.Might play a role in transcription regulation.The 20S PRMT5-containing methyltransferase complex also methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4),methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage.

Aliases: 2610312E17Rik, Androgen receptor cofactor p44, C79984, HKMT1069, MEP 50, MEP-50, MEP50, MEP50_HUMAN, Methylosome protein 50, MGC2722, Nbla10071, p44, p44/Mep50, RGD1310479, RP11 552M11.3, WD repeat containing protein 77, WD repeat domain 77,

UniProt: Q9BQA1

Pathways: Ribonucleoprotein Complex Subunit Organization