PRKAB1 Antikörper

Produktnummer ABIN7140293

Dieses Maus Monoklonal-Antikörper erkennt spezifisch PRKAB1 in WB, IHC, ELISA, ICC und IP. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für PRKAB1 Antikörper (ABIN7140293)

Target: PRKAB1 (Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PRKAB1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Immunoprecipitation (IP)

Produktdetails anti-PRKAB1 Antikörper

Kreuzreaktivität: Human, Affe, Maus, Ratte

Aufreinigung: Affinity purified

Immunogen: Purified recombinant human AMPK beta 1 protein fragments expressed in E.coli.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution:WB:1:500-1:5000,IHC:1:50-1:500,ICC:1:50-1:200,IP:1:200-1:2000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified mouse monoclonal antibody in PBS( pH 7.4) containing with 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu PRKAB1

Target: PRKAB1 (Protein Kinase, AMP-Activated, beta 1 Non-Catalytic Subunit (PRKAB1))

Andere Bezeichnung: PRKAB1

Hintergrund:

Background: Non-catalytic subunit of AMP-activated protein kinase (AMPK),an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism.In response to reduction of intracellular ATP levels,AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein,carbohydrate and lipid biosynthesis,as well as cell growth and proliferation.AMPK acts via direct phosphorylation of metabolic enzymes,and by longer-term effects via phosphorylation of transcription regulators.Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton,probably by indirectly activating myosin.Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles,via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1,PRKAG2 or PRKAG3).

Aliases: 1300015D22Rik, 5 AMP activated protein kinase subunit beta 1, 5-AMP-activated protein kinase subunit beta-1, AAKB1_HUMAN, AMP-ACTIVATED PROTEIN KINASE, NONCATALYTIC, BETA-1, AMP-activated, noncatalytic, beta-1, AMPK, AMPK beta 1 chain,

UniProt: Q9Y478

Pathways: AMPK Signaling, Warburg Effekt