GRK2 Antikörper (C-Term)
Kurzübersicht für GRK2 Antikörper (C-Term) (ABIN7140291)
Target
Alle GRK2 (ADRBK1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- C-Term
-
Kreuzreaktivität
- Hund, Human, Maus, Schwein, Ratte
-
Aufreinigung
- Affinity purified
-
Immunogen
- Purified recombinant human ADRBK1(C-term.) protein fragments expressed in E.coli.
-
Isotyp
- IgG1, IgG1 kappa
-
-
-
-
Applikationshinweise
- Recommended dilution:WB:1:500-1:5000,
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine ( pH 7.4, 150 mM NaCl) with 0.2 % sodium azide, 50 %,glycerol
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C,-80 °C
-
Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
-
- GRK2 (ADRBK1) (Adrenergic, Beta, Receptor Kinase 1 (ADRBK1))
-
Andere Bezeichnung
- ADRBK1
-
Hintergrund
-
Background: The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1.
Aliases: GRK2, BARK1, BETA-ARK1
-
UniProt
- P25098
-
Pathways
- EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling
Target
-