FOXO4 Antikörper (AA 45-63)

Produktnummer ABIN7139835

Der Kaninchen Polyklonal Anti-FOXO4-Antikörper wurde für ELISA, IHC und IF validiert. Er ist geeignet, FOXO4 in Proben von Human zu detektieren.

Kurzübersicht für FOXO4 Antikörper (AA 45-63) (ABIN7139835)

Target: FOXO4 (Forkhead Box O4 (FOXO4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FOXO4 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-FOXO4 Antikörper

Bindungsspezifität: AA 45-63

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Peptide sequence from Human Forkhead box protein O4 protein (45-63AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu FOXO4

Target: FOXO4 (Forkhead Box O4 (FOXO4))

Andere Bezeichnung: FOXO4

Hintergrund:

Background: Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle. Involved in increased proteasome activity in embryonic stem cells (ESCs) by activating expression of PSMD11 in ESCs, leading to enhanced assembly of the 26S proteasome, followed by higher proteasome activity.

Aliases: AFX antibody, AFX1 antibody, Afxh antibody, ALL1-fused gene from X chromosome antibody, Fork head domain transcription factor AFX1 antibody, Forkhead box O4 antibody, Forkhead box protein O4 antibody, FOXO 4 antibody, Foxo4 antibody, FOXO4_HUMAN antibody, MGC117660 antibody, MGC120490 antibody, Mixed lineage leukemia, translocated to, 7 antibody, MLLT7 antibody, Myeloid/lymphoid or mixed lineage leukemia (trithorax homolog, Drosophila), translocated to, 7 antibody, Myeloid/lymphoid or mixed lineage leukemia, translocated to, 7 antibody, RGD1561201 antibody

UniProt: P98177

Pathways: Zellzyklus, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Muscle Cell Differentiation