H2AFX Antikörper (pTyr142)
Kurzübersicht für H2AFX Antikörper (pTyr142) (ABIN7139631)
Target
Alle H2AFX Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pTyr142
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Kreuzreaktivität
- Human
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Aufreinigung
- Antigen Affinity Purified
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Immunogen
- Peptide sequence around site of Phospho-Tyr (142) derived from Human Histone H2AX
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Isotyp
- IgG
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anti-H2A Histone Family, Member X (H2AFX) (AA 115-143), (C-Term) antibody
H2AFX Reaktivität: Human WB, IHC (p) Wirt: Maus Monoclonal 938CT5-1-1 unconjugated
anti-H2A Histone Family, Member X (H2AFX) (pSer139) antibodyH2AFX Reaktivität: Human, Maus WB, BI Wirt: Maus Monoclonal N1-431 unconjugated
anti-H2A Histone Family, Member X (H2AFX) (pSer139) antibodyH2AFX Reaktivität: Human WB, ELISA, IF, ChIP Wirt: Kaninchen Polyclonal unconjugated
anti-H2A Histone Family, Member X (H2AFX) (pSer140) antibodyH2AFX Reaktivität: Human WB, ELISA, IHC (p), ICC, FACS, IF (p), IF (cc), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-H2A Histone Family, Member X (H2AFX) (ubLys119) antibodyH2AFX Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p), ICC, IF (p), IF (cc), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-H2A Histone Family, Member X (H2AFX) (pSer139) antibodyH2AFX Reaktivität: Human WB, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-H2A Histone Family, Member X (H2AFX) antibodyH2AFX Reaktivität: Human WB, IHC (p) Wirt: Maus Monoclonal 8C5 unconjugated
anti-H2A Histone Family, Member X (H2AFX) (AA 1-30), (N-Term) antibodyH2AFX Reaktivität: Human WB, IHC (p) Wirt: Maus Monoclonal 980CT1-5-5 unconjugated
anti-H2A Histone Family, Member X (H2AFX) (pSer139) antibodyH2AFX Reaktivität: Human WB, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-H2A Histone Family, Member X (H2AFX) (C-Term) antibodyH2AFX Reaktivität: Human WB, IF, ICC, ChIP Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- Recommended dilution: IF:1:20-1:200,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- H2AFX (H2A Histone Family, Member X (H2AFX))
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Andere Bezeichnung
- H2AFX
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Hintergrund
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Background: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation.
Aliases: H2A histone family member X antibody, H2A histone family member X antibody, H2A.FX antibody, H2A.X antibody, H2a/x antibody, H2AFX antibody, H2AX antibody, H2AX_HUMAN antibody, Histone H2A.X antibody
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UniProt
- P16104
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Pathways
- Telomere Maintenance, DNA Reparatur, Positive Regulation of Response to DNA Damage Stimulus
Target
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