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H2AFX Antikörper (H2AXS139ph)

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch H2AFX in WB, ELISA, IF und ChIP. Es zeigt Reaktivität gegenüber Proben von Human.
Produktnummer ABIN7139615
-15% Promotion 2026
298,26 €
350,90 €
Sparen Sie 52,64 € (-15 %)
Zzgl. Versandkosten 20,00 € und MwSt
Lieferung nach: Deutschland
Lieferung in 11 bis 15 Werktagen

Kurzübersicht für H2AFX Antikörper (H2AXS139ph) (ABIN7139615)

Target

Alle H2AFX Antikörper anzeigen
H2AFX (H2A Histone Family, Member X (H2AFX))

Reaktivität

  • 207
  • 109
  • 87
  • 25
  • 25
  • 19
  • 17
  • 11
  • 8
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Human

Wirt

  • 180
  • 27
  • 2
  • 2
Kaninchen

Klonalität

  • 120
  • 91
Polyklonal

Konjugat

  • 120
  • 10
  • 8
  • 8
  • 7
  • 6
  • 6
  • 6
  • 6
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Dieser H2AFX Antikörper ist unkonjugiert

Applikation

  • 171
  • 88
  • 66
  • 55
  • 44
  • 32
  • 32
  • 27
  • 27
  • 16
  • 8
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Chromatin Immunoprecipitation (ChIP)
  • Bindungsspezifität

    • 51
    • 21
    • 18
    • 10
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    H2AXS139ph

    Verwendungszweck

    Phospho-H2AFX (S139) Antibody

    Aufreinigung

    Antigen Affinity Purified

    Immunogen

    Peptide sequence around site of Phospho-Ser (139) derived from Human Histone H2AX

    Isotyp

    IgG
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C,-80 °C

    Informationen zur Lagerung

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target

    H2AFX (H2A Histone Family, Member X (H2AFX))

    Andere Bezeichnung

    H2AFX

    Hintergrund

    Background: Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C-terminal phosphorylation.

    Aliases: H2A histone family member X antibody, H2A histone family member X antibody, H2A.FX antibody, H2A.X antibody, H2a/x antibody, H2AFX antibody, H2AX antibody, H2AX_HUMAN antibody, Histone H2A.X antibody

    UniProt

    P16104

    Pathways

    Telomere Maintenance, DNA Reparatur, Positive Regulation of Response to DNA Damage Stimulus
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