HCK Antikörper (pTyr521)

Produktnummer ABIN7139019

Produktdetails anti-HCK Antikörper

Target: HCK (Hemopoietic Cell Kinase (HCK))

Bindungsspezifität: pTyr521

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HCK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of tyrosine 521(E-S-Q(p)-Y-Q) derived from Human HCK .

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB:1:500-1:1000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu HCK

Target: HCK (Hemopoietic Cell Kinase (HCK))

Andere Bezeichnung: HCK (HCK Produkte)

Synonyme: laloo antikoerper, HCK antikoerper, MGC107870 antikoerper, JTK9 antikoerper, p59Hck antikoerper, p61Hck antikoerper, AI849071 antikoerper, Bmk antikoerper, Hctk antikoerper, p56Hck antikoerper, HCK proto-oncogene, Src family tyrosine kinase L homeolog antikoerper, HCK proto-oncogene, Src family tyrosine kinase antikoerper, hemopoietic cell kinase antikoerper, hck.L antikoerper, HCK antikoerper, hck antikoerper, Hck antikoerper

Hintergrund:

Background:

The protein encoded by this gene is a protein-tyrosine kinase that is predominantly expressed in hemopoietic cell types. The encoded protein may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Alternate translation initiation site usage, including a non-AUG (CUG) codon, results in the production of two different isoforms, that have different subcellular localization.

Quintrell N., Mol. Cell. Biol. 7:2267-2275(1987) [PubMed: 3496523].
Ziegler S.F.,Mol. Cell. Biol. 7:2276-2285(1987) [PubMed: 3453117].
Ota T., Nat. Genet. 36:40-45(2004) [PubMed: 14702039].

Aliases: Bmk antibody, Hck 1 antibody, Hck antibody, HCK_HUMAN antibody, Hemopoietic cell kinase antibody, JTK9 antibody, p59-HCK/p60-HCK antibody, p59Hck antibody, p59HCK/p60HCK antibody, p61Hck antibody, Tyrosine protein kinase HCK antibody, Tyrosine-protein kinase HCK antibody

UniProt: P08631

Pathways: Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling