DOK2 Antikörper (pTyr299)
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- Target Alle DOK2 Antikörper anzeigen
- DOK2
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Bindungsspezifität
- pTyr299
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser DOK2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Kreuzreaktivität
- Human
- Aufreinigung
- Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi
- Immunogen
- Peptide sequence around phosphorylation site of tyrosine 299 (G-E-Y(p)-A-V) derived from Human p56Dok-2.
- Isotyp
- IgG
- Top Product
- Discover our top product DOK2 Primärantikörper
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- Applikationshinweise
- WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- DOK2
- Andere Bezeichnung
- DOK2 (DOK2 Produkte)
- Hintergrund
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Background:
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK2 may modulate the cellular proliferation induced by IL-4, as well as IL-2 and IL-3. May be involved in modulating Bcr-Abl signaling. Attenuates EGF-stimulated MAP kinase activation
Feng Cong, et,al. (1999) Mol. Cell. Biol , 19: 8314 - 8325.
Serge Lemay, et,al. (2000) Mol. Cell. Biol , 20: 2743 - 2754.
Ute Schaeper, et,al.(2000) J. Cell Biol , 149: 1419.
Miyuki Honma, et,al. (2006) Genes Cells, 11: 143 - 151.Aliases: Docking protein 2 56 kDa antibody, Docking protein 2 antibody, DOK 2 antibody, DOK R antibody, DOK2 antibody, DOK2_HUMAN antibody, Downstream of tyrosine kinase 2 antibody, OTTHUMP00000161710 antibody, OTTHUMP00000224923 antibody, p56(dok 2) antibody, p56(dok-2) antibody, p56dok 2 antibody, p56DOK antibody, p56dok2 antibody
- UniProt
- O60496
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