Phospholipase D2 Antikörper (pTyr169)

Produktnummer ABIN7138945

Dieses Anti-Phospholipase D2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Phospholipase D2 in WB, ELISA und IHC. Geeignet für Human.

Kurzübersicht für Phospholipase D2 Antikörper (pTyr169) (ABIN7138945)

Target: Phospholipase D2 (PLD2)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Phospholipase D2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-Phospholipase D2 Antikörper

Bindungsspezifität: pTyr169

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of tyrosine 169(E-N-Y(p)-L-N) derived from Human PLD2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB:1:500-1:1000, IHC:1:50-1:100,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu Phospholipase D2

Target: Phospholipase D2 (PLD2)

Andere Bezeichnung: PLD2

Hintergrund:

Background:

Phosphatidylcholine (PC)-specific phospholipases D (PLDs) catalyze the hydrolysis of PC to produce phosphatidic acid and choline. Activation of PC-specific PLDs occurs as a consequence of agonist stimulation of both tyrosine kinase and G protein-coupled receptors. PC-specific PLDs have been proposed to function in regulated secretion, cytoskeletal reorganization, transcriptional regulation, and cell cycle control.

Steed P.M., FASEB J. 12:1309-1317(1998).
Lopez I., J. Biol. Chem. 273:12846-12852(1998).
Divecha N., EMBO J. 19:5440-5449(2000).

Aliases: Choline phosphatase 2 antibody, EC 3.1.4.4 antibody, hPLD 2 antibody, hPLD2 antibody, mPLD2 antibody, Phosphatidylcholine hydrolyzing phospholipase D2 antibody, Phosphatidylcholine-hydrolyzing phospholipase D2 antibody, Phospholipase D2 antibody, PhospholipaseD2 antibody, PLD 2 antibody, PLD1C antibody, Pld2 antibody, PLD2_HUMAN antibody, Pldc antibody, rPLD2 antibody

UniProt: O14939

Pathways: RTK Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Regulation of G-Protein Coupled Receptor Protein Signaling