ERBB3 Antikörper (pTyr1328)

Produktnummer ABIN7138931

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch ERBB3 in WB, ELISA, IHC und IF. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für ERBB3 Antikörper (pTyr1328) (ABIN7138931)

Target: ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ERBB3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-ERBB3 Antikörper

Bindungsspezifität: pTyr1328

Verwendungszweck: Phospho-ERBB3 (Tyr1328) Antibody

Kreuzreaktivität: Maus, Ratte

Aufreinigung: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of tyrosine 1328 (P-D-Y(p)-W-H) derived from Human Her3/ErbB3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu ERBB3

Target: ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))

Andere Bezeichnung: ERBB3

Hintergrund:

Background: Binds and is activated by neuregulins and NTAK.

Holbro, T. et al. (2003) Proc. Natl. Acad. Sci. USA 100, 8933-8938.
Kobayashi, M. et al. (2003) Oncogene 22, 1294-1301.
Kim, H.H. et al. (1994) J. Biol. Chem. 269, 24747-24755.
Yarden, Y. and Sliwkowski, M.X. (2001) Nature Rev. Mol. Cell. Biol. 2, 127-137.

Aliases: c erbB 3 antibody, c erbB3 antibody, Erb b2 receptor tyrosine kinase 3 antibody, ErbB 3 antibody, ERBB3 antibody, ERBB3 protein antibody, erbB3 S antibody, ERBB3_HUMAN antibody, Glial growth factor receptor antibody, HER 3 antibody, HER3 antibody, Human epidermal growth factor receptor 3 antibody, LCCS2 antibody, MDA BF 1 antibody, MGC88033 antibody, p180 ErbB3 antibody, p45 sErbB3 antibody, p85 sErbB3 antibody, proto-oncogene-like protein c ErbB 3 antibody, proto-oncogene-like protein c ErbB3 antibody, Proto-oncogene-like protein c-ErbB-3 antibody, Receptor tyrosine protein kinase erbB 3 antibody, Receptor tyrosine protein kinase erbB3 antibody, Receptor tyrosine-protein kinase erbB-3 antibody, Tyrosine kinase type cell surface receptor HER3 antibody, Tyrosine kinase-type cell surface receptor HER3 antibody, v erb b2 avian erythroblastic leukemia viral oncogene homolog 3 antibody, v erb b2 erythroblastic leukemia viral oncogene homolog 3 (avian) antibody, v erb b2 erythroblastic leukemia viral oncogene homolog 3 antibody

UniProt: P21860

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung