SUFUH Antikörper (pSer342)

Produktnummer ABIN7138564

Dieses Anti-SUFUH-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SUFUH in WB und ELISA. Geeignet für Human.

Kurzübersicht für SUFUH Antikörper (pSer342) (ABIN7138564)

Target: SUFUH (Suppressor of Fused Homolog (SUFUH))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SUFUH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-SUFUH Antikörper

Bindungsspezifität: pSer342

Kreuzreaktivität: Human

Aufreinigung: Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogen: Peptide sequence around phosphorylation site of Serine 342 (A-P-S(p)-R-K) derived from Human Sufu.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB:1:500-1:1000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu SUFUH

Target: SUFUH (Suppressor of Fused Homolog (SUFUH))

Andere Bezeichnung: SUFU

Hintergrund:

Background: SUFU encodes a component of the Sonic hedgehog (SHH, MIM 600725)/Patched (PTCH, MIM 601309) signaling pathway. Mutations in genes encoding components of this pathway are deleterious for normal development and are associated with cancer-predisposing syndromes (e.g., HPE3, MIM 142945, BCNS, MIM 109400, and GCPS, MIM 175700)

Zimmern P,et al.(2010) Neurourol Urodyn.29(5):715-8.
Wang C,et al. (2010) Development. 137(12):2001-9.
Rabasseda X.et al.(2010) Drug News Perspect.23(4):273-5.

Aliases: OTTHUMP00000020374 antibody, OTTHUMP00000020377 antibody, OTTHUMP00000020379 antibody, PRO1280 antibody, SU FU antibody, SU(F)U antibody, Su(fu) antibody, SUFU antibody, SUFU negative regulator of hedgehog signaling antibody, SUFU_HUMAN antibody, SUFUH antibody, SUFUXL antibody, Suppressor of Fused antibody, Suppressor of fused homolog (Drosophila) antibody, Suppressor of fused homolog antibody

UniProt: Q9UMX1

Pathways: Hedgehog Signalweg, Tube Formation, Maintenance of Protein Location