HNRNPC Antikörper (pSer260)

Produktnummer ABIN7138520

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch HNRNPC in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für HNRNPC Antikörper (pSer260) (ABIN7138520)

Target: HNRNPC (Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HNRNPC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-HNRNPC Antikörper

Bindungsspezifität: pSer260

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Immunogen: Peptide sequence around phosphorylation site of Serine 260(D-D-S(p)-A-E) derived from Human hnRNP C1/2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB:1:500-1:1000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu HNRNPC

Target: HNRNPC (Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC))

Andere Bezeichnung: HNRNPC

Hintergrund:

Background: Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles. Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides. May play a role in the early steps of spliceosome assembly and pre-mRNA splicing. Interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules.

Aliases: C1 antibody, C2 antibody, Heterogeneous nuclear ribonucleoprotein C (C1/C2) antibody, Heterogeneous nuclear ribonucleoprotein C antibody, Heterogeneous nuclear ribonucleoproteins C1/C2 antibody, HNRNP antibody, hnRNP C1 / hnRNP C2 antibody, hnRNP C1/C2 antibody, Hnrnpc antibody, HNRPC antibody, HNRPC_HUMAN antibody, MGC104306 antibody, MGC105117 antibody, MGC117353 antibody, MGC131677 antibody, Nuclear ribonucleoprotein particle C1 protein antibody, Nuclear ribonucleoprotein particle C2 protein antibody, SNRPC antibody

UniProt: P07910