Oncostatin M Receptor Antikörper

Produktnummer ABIN709616

Produktdetails anti-Oncostatin M Receptor Antikörper

Target: Oncostatin M Receptor (OSMR)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Oncostatin M Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Oncostatin-M receptor

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu Oncostatin M Receptor

Target: Oncostatin M Receptor (OSMR)

Andere Bezeichnung: Osmr (OSMR Produkte)

Synonyme: OSMRB antikoerper, PLCA1 antikoerper, oncostatin M receptor antikoerper, OSMR antikoerper, Osmr antikoerper

Hintergrund:

Synonyms: Oncostatin M receptor, Oncostatin M specic receptor subunit beta, Interleukin-31 receptor subunit beta, IL-31 receptor subunit beta, IL-31R subunit beta, IL-31R-beta, IL-31RB, Oncostatin-M-specic receptor, beta, OSMRB, MGC140467, MGC150626, MGC150627, MGC75127.

Background: Oncostatin M is a member of the IL6 family of cytokines. Functional receptors for IL6 family cytokines are multisubunit complexes involving members of the hematopoietin receptor superfamily. Many IL6 cytokines utilize gp130 as a common receptor subunit. OSM binds to the gp130 receptor subunit and, in association with the leukemia inhibitory factor receptor, induces a proliferative response in permissive cells. OSMR is an alternative subunit (for an OSM receptor complex (a heterodimer of gp130 and OSMR) that is activated by OSM but not by LIF.

Gen-ID: 157869

Pathways: JAK-STAT Signalweg, Growth Factor Binding