SMAD1 Antikörper (AA 461-465)
Kurzübersicht für SMAD1 Antikörper (AA 461-465) (ABIN7138266)
Target
Alle SMAD1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 461-465
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Kreuzreaktivität
- Human, Maus, Ratte
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Aufreinigung
- Affinity purification
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Immunogen
- Peptide sequence around aa.461-465(I-S-S-V-S) derived from Human Smad1. This sequence has the same homology in Smad5 and Smad8.
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Isotyp
- IgG
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Applikationshinweise
- WB:1:500-1:1000,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified Rabbit polyclonal in PBS( pH 7.4) containing with 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- SMAD1 (SMAD, Mothers Against DPP Homolog 1 (SMAD1))
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Andere Bezeichnung
- SMAD1
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Hintergrund
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Background: Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD).SMAD5 is a receptor-regulated SMAD (R-SMAD). SMAD9 is a receptor-regulated SMAD (R-SMAD). Has been shown to be activated by activin type I receptor-like kinases (ALK-2, ALK-3, ALK-6) which stimulate heteromerization between SMAD9 and SMAD4. May play a role in osteoblast differentiation and maturation.
Aliases: Mad-related protein 1, SMAD 1, hSMAD1, Transforming growth factor-beta-signaling protein 1
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UniProt
- Q15797
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Pathways
- Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
Target
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