HDAC4 Antikörper
Kurzübersicht für HDAC4 Antikörper (ABIN7138137)
Target
Alle HDAC4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- HDAC4/HDAC5/HDAC9 (Ab-246/259/220) Antibody
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Kreuzreaktivität
- Maus
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Aufreinigung
- Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
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Immunogen
- Peptide sequence around aa.244~248/257~261/218~222 (T-A-S-E-P) derived from Human HDAC4/HDAC5/HDAC9.
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Isotyp
- IgG
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anti-Histone Deacetylase 4 (HDAC4) (AA 904-1076) antibody
HDAC4 Reaktivität: Maus WB, IHC, IP, ICC, FACS Wirt: Kaninchen Polyclonal unconjugated
anti-Histone Deacetylase 4 (HDAC4) (AA 456-592) antibodyHDAC4 Reaktivität: Human ELISA, ICC, FACS Wirt: Maus Monoclonal 7E2E6 unconjugated
anti-Histone Deacetylase 4 (HDAC4) (AA 456-592) antibodyHDAC4 Reaktivität: Human ELISA, IHC, FACS Wirt: Maus Monoclonal 5E4A5 unconjugated
anti-Histone Deacetylase 4 (HDAC4) (AA 551-648) antibodyHDAC4 Reaktivität: Human WB, ELISA, IF, IHC (p) Wirt: Maus Monoclonal 2B11 unconjugated
anti-Histone Deacetylase 4 (HDAC4) (AA 451-650) antibodyHDAC4 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Histone Deacetylase 4 (HDAC4) (AA 1049-1077) antibodyHDAC4 Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Histone Deacetylase 4 (HDAC4) (AA 530-630) antibodyHDAC4 Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Histone Deacetylase 4 (HDAC4) (pSer220), (pSer246), (pSer259) antibodyHDAC4 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Histone Deacetylase 4 (HDAC4) (AA 1049-1077), (C-Term) antibodyHDAC4 Reaktivität: Human WB, IF, IHC (p) Wirt: Kaninchen Polyclonal RB33667 unconjugated
anti-Histone Deacetylase 4 (HDAC4) antibodyHDAC4 Reaktivität: Human, Maus, Ratte IHC Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Supplied at 1.0 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- HDAC4 (Histone Deacetylase 4 (HDAC4))
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Andere Bezeichnung
- HDAC4
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Hintergrund
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Background:
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D.
Cress, W.D. and Seto, E. (2000) J Cell Physiol 184, 1-16.
Vigushin, D.M. and Coombes, R.C. (2004) Curr. Cancer Drug Targets 4, 205-218.
Marmorstein, R. (2001) Cell Mol Life Sci 58, 693-703.
Thiagalingam, S. et al. (2003) Ann. N.Y. Acad. Sci. 983, 84-100.Aliases: HD4/HD5/HD9
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UniProt
- P56524, Q9UQL6, Q9UKV0
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Pathways
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process
Target
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