PRCP Antikörper

Produktnummer ABIN7130695

Dieses Anti-PRCP-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von PRCP in WB, IHC und ELISA. Geeignet für Human.

Kurzübersicht für PRCP Antikörper (ABIN7130695)

Target: PRCP (Prolylcarboxypeptidase (PRCP))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRCP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-PRCP Antikörper

Kreuzreaktivität: Human, Maus

Aufreinigung: Antigen affinity purification

Immunogen: Fusion protein of Human PRCP

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu PRCP

Target: PRCP (Prolylcarboxypeptidase (PRCP))

Andere Bezeichnung: PRCP

Hintergrund:

Background: The protein encoded by this gene is a lysosomal prolylcarboxypeptidase, which cleaves C-terminal amino acids linked to proline in peptides such as angiotension II, III and des-Arg9-bradykinin. The cleavage occurs at acidic pH , but the enzyme activity is retained with some substrates at neutral pH . This enzyme has been shown to be an activator of the cell matrix-associated prekallikrein. The importance of angiotension II, one of the substrates of this enzyme, in regulating blood pressure and electrolyte balance suggests that this gene may be related to essential hypertension. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Aliases: Angiotensinase C antibody, HUMPCP antibody, Lysosomal carboxypeptidase C antibody, Lysosomal Pro X carboxypeptidase antibody, Lysosomal Pro-X carboxypeptidase antibody, MGC2202 antibody, PCP antibody, PCP_HUMAN antibody, PRCP antibody, Proline carboxypeptidase antibody, Prolylcarboxypeptidase (angiotensinase C) antibody, Prolylcarboxypeptidase antibody, prolylcarboxypeptidase isoform 1 preproprotein antibody

UniProt: P42785