OPTN Antikörper

Produktnummer ABIN7130502

Der Kaninchen Polyklonal anti-OPTN Antikörper wird verwendet zum Nachweis von OPTN in Proben von Human. Er wurde validiert für IHC und ELISA.

Kurzübersicht für OPTN Antikörper (ABIN7130502)

Target: OPTN (Optineurin (OPTN))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser OPTN Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA

Produktdetails anti-OPTN Antikörper

Verwendungszweck: OPTN Antibody

Kreuzreaktivität: Maus, Ratte

Aufreinigung: Antigen affinity purification

Immunogen: Fusion protein of Human OPTN

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer:  pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu OPTN

Target: OPTN (Optineurin (OPTN))

Andere Bezeichnung: OPTN

Hintergrund:

Background: This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins.

Aliases: 14.7K interacting protein antibody, Ag9 C5 antibody, ALS12 antibody, E3 14.7K interacting protein antibody, E3-14.7K-interacting protein antibody, FIP 2 antibody, FIP-2 antibody, FIP2 antibody, Glaucoma 1 open angle E (adult onset) antibody, Glaucoma 1 open angle E antibody, GLC1E antibody, HIP 7 antibody, HIP-7 antibody, HIP7 antibody, Huntingtin interacting protein 7 antibody, Huntingtin interacting protein HYPL antibody, Huntingtin interacting protein L antibody, Huntingtin yeast partner L antibody, Huntingtin-interacting protein 7 antibody, Huntingtin-interacting protein L antibody, HYPL antibody, Injury inducible protein I 55 antibody, NEMO related protein antibody, NEMO-related protein antibody, NRP antibody, Optic neuropathy inducing protein antibody, Optic neuropathy-inducing protein antibody, Optineurin antibody, OPTN antibody, OPTN_HUMAN antibody, TFIIIA IntP antibody, TFIIIA-IntP antibody, Transcription factor IIIA interacting protein antibody, Transcription factor IIIA-interacting protein antibody, Tumor necrosis factor alpha inducible cellular protein containing leucine zipper domains antibody

UniProt: Q96CV9

Pathways: M Phase