MGEA5 Antikörper

Produktnummer ABIN7130225

Produktdetails anti-MGEA5 Antikörper

Target: MGEA5 (Meningioma Expressed Antigen 5 (Hyaluronidase) (MGEA5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MGEA5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Antigen affinity purification

Immunogen: Fusion protein of Human MGEA5

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu MGEA5

Target: MGEA5 (Meningioma Expressed Antigen 5 (Hyaluronidase) (MGEA5))

Andere Bezeichnung: MGEA5 (MGEA5 Produkte)

Hintergrund:

Background: The dynamic modification of cytoplasmic and nuclear proteins by O-linked N-acetylglucosamine (O-GlcNAc) addition and removal on serine and threonine residues is catalyzed by OGT, which adds O-GlcNAc, and MGEA5, a glycosidase that removes O-GlcNAc modifications. Cleaves GlcNAc but not GalNAc from glycopeptides. Can use p-nitrophenyl-beta-GlcNAc as substrate but not p-nitrophenyl-beta-GalNAc or p-nitrophenyl-alpha-GlcNAc. Possesses hyaluronidase activity. Acetylates 'Lys-8' of histone H4 and 'Lys-14' of histone H3. Shows highest expression in the brain, placenta and pancreas.

Aliases: Beta-hexosaminidase antibody, Beta-N-acetylglucosaminidase antibody, Beta-N-acetylhexosaminidase antibody, Bifunctional protein NCOAT antibody, HEXC antibody, Hyaluronidase in meningioma antibody, KIAA0679 antibody, MEA5 antibody, Meningioma expressed antigen 5 antibody, Meningioma-expressed antigen 5 antibody, MGEA 5 antibody, Mgea5 antibody, N-acetyl-beta-D-glucosaminidase antibody, N-acetyl-beta-glucosaminidase antibody, NCOAT antibody, Nuclear cytoplasmic O GlcNAcase and acetyltransferase antibody, Nuclear cytoplasmic O-GlcNAcase and acetyltransferase antibody, OGA antibody, OGA_HUMAN antibody, Protein O-GlcNAcase antibody

UniProt: O60502

Pathways: Positive Regulation of Peptide Hormone Secretion, Regulation of Carbohydrate Metabolic Process