CNTF Receptor alpha Antikörper (AA 23-342)

Produktnummer ABIN7128092

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CNTF Receptor alpha in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CNTF Receptor alpha Antikörper (AA 23-342) (ABIN7128092)

Target: CNTF Receptor alpha (CNTFR) (Ciliary Neurotrophic Factor Receptor (CNTFR))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CNTF Receptor alpha Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-CNTF Receptor alpha Antikörper

Bindungsspezifität: AA 23-342

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Affinity purification

Immunogen: Fusion protein corresponding to a region derived from 23-342 amino acids of Human ciliary neurotrophic factor receptor

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB:1:500-1:2000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied at 0.5 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.3, 0.05 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CNTF Receptor alpha

Target: CNTF Receptor alpha (CNTFR) (Ciliary Neurotrophic Factor Receptor (CNTFR))

Andere Bezeichnung: CNTFR

Hintergrund:

Background:

This gene encodes a member of the type 1 cytokine receptor family. The encoded protein is the ligand-specific component of a tripartite receptor for ciliary neurotrophic factor, which plays a critical role in neuronal cell survival, differentiation and gene expression. Binding of ciliary neurotrophic factor to the encoded protein recruits the transmembrane components of the receptor, gp130 and leukemia inhibitory factor receptor, facilitating signal transduction. Single nucleotide polymorphisms in this gene may be associated with variations in muscle strength, as well as early onset of eating disorders. Alternatively spliced transcript variants have been observed for this gene.

Aliases: Ciliary neurotrophic factor receptor alpha antibody, Ciliary neurotrophic factor receptor antibody, Ciliary neurotrophic factor receptor subunit alpha antibody, CNTF Receptor alpha antibody, CNTF receptor subunit alpha antibody, CNTFR Alpha antibody, CNTFR antibody, CNTFR-alpha antibody, CNTFR_HUMAN antibody

UniProt: P26992

Pathways: JAK-STAT Signalweg, Feeding Behaviour