Rekombinanter TINF2 Antikörper
Kurzübersicht für Rekombinanter TINF2 Antikörper (ABIN7127845)
Target
Alle TINF2 (TIN2) Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Kreuzreaktivität
- Human, Maus, Ratte
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Aufreinigung
- Affinity-chromatography
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Immunogen
- A synthesized peptide derived from human Tin2
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Isotyp
- IgG
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Applikationshinweise
- Recommended dilution: WB:1:500-1:5000,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- TINF2 (TIN2) (TERF1 Interacting Nuclear Factor 2 (TIN2))
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Andere Bezeichnung
- TINF2
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Hintergrund
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Background: Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends, without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Plays a role in shelterin complex assembly. Isoform 1 may have additional role in tethering telomeres to the nuclear matrix.
Aliases: TERF1-interacting nuclear factor 2 (TRF1-interacting nuclear protein 2), TINF2, TIN2
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UniProt
- Q9BSI4
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Pathways
- Zellzyklus, Telomere Maintenance, Regulation of Carbohydrate Metabolic Process
Target
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