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Rekombinanter SMC1A Antikörper

This anti-SMC1A antibody (ABIN7127813) is a Rabbit Monoclonal antibody detecting SMC1A in WB, IHC, ELISA. Suitable for Human.
Produktnummer ABIN7127813

Quick Overview for Rekombinanter SMC1A Antikörper (ABIN7127813)

Target

Alle SMC1A Antikörper anzeigen
SMC1A (Structural Maintenance of Chromosomes 1A (SMC1A))

Antikörpertyp

Recombinant Antibody

Reaktivität

  • 135
  • 57
  • 25
  • 7
  • 7
  • 6
  • 5
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
Human

Wirt

  • 116
  • 14
  • 4
  • 1
Kaninchen

Klonalität

  • 100
  • 35
Monoklonal

Konjugat

  • 72
  • 7
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
Dieser SMC1A Antikörper ist unkonjugiert

Applikation

  • 101
  • 39
  • 30
  • 29
  • 28
  • 23
  • 20
  • 13
  • 12
  • 9
  • 7
  • 5
  • 4
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Klon

8C11
  • Kreuzreaktivität

    Human

    Aufreinigung

    Affinity-chromatography

    Immunogen

    A synthesized peptide derived from human SMC1

    Isotyp

    IgG
  • Applikationshinweise

    Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200,

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C,-80 °C

    Informationen zur Lagerung

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target

    SMC1A (Structural Maintenance of Chromosomes 1A (SMC1A))

    Andere Bezeichnung

    SMC1A

    Hintergrund

    Background: Involved in chromosome cohesion during cell cycle and in DNA repair. Central component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis. Involved in DNA repair via its interaction with BRCA1 and its related phosphorylation by ATM, or via its phosphorylation by ATR. Works as a downstream effector both in the ATM/NBS1 branch and in the ATR/MSH2 branch of S-phase checkpoint.

    Aliases: Structural maintenance of chromosomes protein 1A (SMC protein 1A) (SMC-1-alpha) (SMC-1A) (Sb1.8), SMC1A, DXS423E KIAA0178 SB1.8 SMC1 SMC1L1

    UniProt

    Q14683

    Pathways

    Stem Cell Maintenance
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