Rekombinanter SMAD2 Antikörper (pSer255)
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- Target Alle SMAD2 Antikörper anzeigen
- SMAD2 (SMAD, Mothers Against DPP Homolog 2 (SMAD2))
- Antikörpertyp
- Recombinant Antibody
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Bindungsspezifität
- pSer255
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Monoklonal
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Konjugat
- Dieser SMAD2 Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunofluorescence (IF)
- Kreuzreaktivität
- Human
- Aufreinigung
- Affinity-chromatography
- Immunogen
- A synthesized peptide derived from human Phospho-SMAD2 (S255)
- Klon
- 2A12
- Isotyp
- IgG
- Top Product
- Discover our top product SMAD2 Primärantikörper
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- Applikationshinweise
- Recommended dilution: IF:1:20-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- SMAD2 (SMAD, Mothers Against DPP Homolog 2 (SMAD2))
- Andere Bezeichnung
- SMAD2 (SMAD2 Produkte)
- Synonyme
- JV18 antikoerper, JV18-1 antikoerper, MADH2 antikoerper, MADR2 antikoerper, hMAD-2 antikoerper, hSMAD2 antikoerper, jv18 antikoerper, Xmad2 antikoerper, madh2 antikoerper, madr2 antikoerper, XSmad2 antikoerper, hmad-2 antikoerper, hsmad2 antikoerper, jv18-1 antikoerper, smad-2 antikoerper, fj43c06 antikoerper, wu:fj43c06 antikoerper, 7120426M23Rik antikoerper, Madh2 antikoerper, Madr2 antikoerper, Smad-2 antikoerper, mMad2 antikoerper, MAD homolog 2 antikoerper, Mothers against DPP homolog 2 antikoerper, SMAD 2 antikoerper, Smad2 antikoerper, SMAD family member 2 antikoerper, SMAD family member 2-Z antikoerper, SMAD family member 2 S homeolog antikoerper, SMAD2 antikoerper, SMAD2Z antikoerper, smad2 antikoerper, smad2.S antikoerper, Smad2 antikoerper
- Hintergrund
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Background: Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator.
Aliases: Mothers against decapentaplegic homolog 2, MAD homolog 2, Mothers against DPP homolog 2, JV18-1, Mad-related protein 2, hMAD-2, SMAD family member 2, SMAD 2, Smad2, hSMAD2, SMAD2, MADH2, MADR2
- UniProt
- Q15796
- Pathways
- Zellzyklus, Hormone Transport, Chromatin Binding, Protein targeting to Nucleus
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