Rekombinanter MLKL Antikörper (pSer358)
Kurzübersicht für Rekombinanter MLKL Antikörper (pSer358) (ABIN7127713)
Target
Alle MLKL Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- pSer358
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Kreuzreaktivität
- Human
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Aufreinigung
- Affinity-chromatography
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Immunogen
- A synthesized peptide derived from human Phospho-MLKL (S358)
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Isotyp
- IgG
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Applikationshinweise
- Recommended dilution: IHC:1:50-1:200,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- MLKL (Mixed Lineage Kinase Domain-Like (MLKL))
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Andere Bezeichnung
- MLKL
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Hintergrund
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Background: Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.
Aliases: Mixed lineage kinase domain-like protein, hMLKL, MLKL
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UniProt
- Q8NB16
Target
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