MLKL Antikörper (Internal Region)
(1 reference)-
- Target Alle MLKL Antikörper anzeigen
- MLKL (Mixed Lineage Kinase Domain-Like (MLKL))
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Bindungsspezifität
- Internal Region
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MLKL Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Spezifität
- MLKL Antibody detects endogenous levels of total MLKL.
- Aufreinigung
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- Immunogen
- A synthesized peptide derived from human MLKL, corresponding to a region within the internal amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product MLKL Primärantikörper
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anti-Mixed Lineage Kinase Domain-Like (MLKL) antibody
MLKL Reaktivität: Human, Maus, Ratte IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Mixed Lineage Kinase Domain-Like (MLKL) (AA 371-471) antibodyMLKL Reaktivität: Human WB, ELISA, IHC (p), IF Wirt: Maus Monoclonal 3B2 unconjugated
anti-Mixed Lineage Kinase Domain-Like (MLKL) (AA 444-472) antibodyMLKL Reaktivität: Maus WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Mixed Lineage Kinase Domain-Like (MLKL) (AA 1-471) antibodyMLKL Reaktivität: Human WB, IF Wirt: Maus Polyclonal unconjugated
anti-Mixed Lineage Kinase Domain-Like (MLKL) (C-Term) antibodyMLKL Reaktivität: Maus WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Mixed Lineage Kinase Domain-Like (MLKL) (pSer358) antibodyMLKL Reaktivität: Human IHC (p) Wirt: Maus Monoclonal 6E3 unconjugated
anti-Mixed Lineage Kinase Domain-Like (MLKL) antibodyMLKL Reaktivität: Human ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Mixed Lineage Kinase Domain-Like (MLKL) (AA 371-472) antibodyMLKL Reaktivität: Human WB, ELISA, IHC, IHC (p) Wirt: Maus Monoclonal 3B2 unconjugated
anti-Mixed Lineage Kinase Domain-Like (MLKL) antibodyMLKL Reaktivität: Maus WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Mixed Lineage Kinase Domain-Like (MLKL) antibodyMLKL Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20 °C. Stable for 12 months from date of receipt.
- Haltbarkeit
- 12 months
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: "Alterations in necroptosis during ALDH2‑mediated protection against high glucose‑induced H9c2 cardiac cell injury." in: Molecular medicine reports, Vol. 18, Issue 3, pp. 2807-2815, (2018) (PubMed).
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: "Alterations in necroptosis during ALDH2‑mediated protection against high glucose‑induced H9c2 cardiac cell injury." in: Molecular medicine reports, Vol. 18, Issue 3, pp. 2807-2815, (2018) (PubMed).
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- Target
- MLKL (Mixed Lineage Kinase Domain-Like (MLKL))
- Andere Bezeichnung
- MLKL (MLKL Produkte)
- Synonyme
- MLKL antikoerper, 9130019I15Rik antikoerper, mixed lineage kinase domain like pseudokinase antikoerper, mixed lineage kinase domain-like antikoerper, MLKL antikoerper, mlkl antikoerper, Mlkl antikoerper
- Hintergrund
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Description: Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.
Gene: MLKL
- Molekulargewicht
- 54kDa
- Gen-ID
- 197259
- UniProt
- Q8NB16
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