Rekombinanter FOXO3 Antikörper
Kurzübersicht für Rekombinanter FOXO3 Antikörper (ABIN7127500)
Target
Alle FOXO3 Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- FOXO3 Recombinant Monoclonal Antibody
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Aufreinigung
- Affinity-chromatography
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Immunogen
- A synthesized peptide derived from human FOXO3
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Isotyp
- IgG
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anti-Forkhead Box O3 (FOXO3) (pSer253) antibody
FOXO3 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (C-Term) antibodyVerified FOXO3 Reaktivität: Human WB, IHC, ELISA Wirt: Ziege Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (pSer318), (pSer321) antibodyFOXO3 Reaktivität: Human, Ratte WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (C-Term) antibodyKO Validated FOXO3 Reaktivität: Human WB, IF, IHC (p), ICC, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (N-Term) antibodyFOXO3 Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Schwein, Schaf, Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio) WB Wirt: Kaninchen Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (N-Term) antibodyFOXO3 Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (AA 361-460) antibodyFOXO3 Reaktivität: Human ELISA, IF, IHC (p) Wirt: Maus Monoclonal 1E11 unconjugated
anti-Forkhead Box O3 (FOXO3) (AA 361-460) antibodyFOXO3 Reaktivität: Human WB, ELISA, IF, IHC (p) Wirt: Maus Monoclonal 1F6 unconjugated
anti-Forkhead Box O3 (FOXO3) (AA 224-253) antibodyFOXO3 Reaktivität: Human WB, IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Forkhead Box O3 (FOXO3) (pSer253) antibodyFOXO3 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- WB:1:500-1:5000, IHC:1:50-1:200, IF:1:20-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- FOXO3 (Forkhead Box O3 (FOXO3))
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Andere Bezeichnung
- FOXO3
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Hintergrund
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Background: Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress (PubMed:10102273, PubMed:16751106). Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3' (PubMed:21329882). Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34c expression, 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation (PubMed:21329882). In response to metabolic stress, translocates into the mitochondria where it promotes mtDNA transcription (PubMed:23283301).
Aliases: Forkhead box protein O3, AF6q21 protein, FOXO3
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UniProt
- O43524
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Pathways
- Zellzyklus, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Carbohydrate Homeostasis
Target
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