Rekombinanter Angiopoietin 2 Antikörper
Kurzübersicht für Rekombinanter Angiopoietin 2 Antikörper (ABIN7127339)
Target
Alle Angiopoietin 2 (ANGPT2) Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Kreuzreaktivität
- Human
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Aufreinigung
- Affinity-chromatography
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Immunogen
- A synthesized peptide derived from human Angiopoietin 2
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Isotyp
- IgG
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Applikationshinweise
- Recommended dilution: IHC:1:50-1:200,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Angiopoietin 2 (ANGPT2)
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Andere Bezeichnung
- ANGPT2
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Hintergrund
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Background: Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal.
Aliases: Angiopoietin-2 (ANG-2), ANGPT2
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UniProt
- O15123
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Pathways
- RTK Signalweg
Target
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