CD79b Antikörper (AA 29-159)
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- Target Alle CD79b (CD79B) Antikörper anzeigen
- CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))
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Bindungsspezifität
- AA 29-159
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD79b Antikörper ist unkonjugiert
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Applikation
- ELISA, Coating (Coat), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- Spezifität
- CD79 (also designated Ig chains, designated CD79B or B29. The B cell antigen receptor complex (BCR) is formed by the association of CD79 with a membrane immunoglobulin, such as IgM or IgD. The membrane immunoglobulins IgM and IgD achieve surface expression and antigen presentation function in response to CD79 association. The cytoplasmic tails of both CD79A and CD79B contain an ITAM (immuno-receptor tyrosine-based activation) motif, which acts to initiate the BCR signaling reactions by binding to and activating tyrosine kinases.
- Kreuzreaktivität (Details)
- Human
- Aufreinigung
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Recombinant fragment of human CD79b protein (around aa 29-159) (exact sequence is proprietary)
- Isotyp
- IgG1
- Top Product
- Discover our top product CD79B Primärantikörper
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- Applikationshinweise
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Known_Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: Daudi or Ramos cells. Germinal center B-cells in a lymph node or tonsil.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Konservierungsmittel
- Azide free
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Haltbarkeit
- 24 months
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- Target
- CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))
- Andere Bezeichnung
- CD79B (CD79B Produkte)
- Synonyme
- B29 antikoerper, Ig-beta antikoerper, Igb antikoerper, Igbeta antikoerper, AGM6 antikoerper, IGB antikoerper, CD79B antigen antikoerper, CD79b molecule antikoerper, Cd79b antikoerper, CD79B antikoerper
- Hintergrund
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AGM6, B-cell antigen receptor complex-associated protein beta chain, B-cell-specific glycoprotein B29, B29, B29/Ig-beta/CD79b, CD79b, Ig-beta, IGB, Immunoglobulin-associated B29 protein,CD79b (B-Cell Marker)
Cellular localisation: Cell Surface - Molekulargewicht
- 39kDa
- Gen-ID
- 974, 89575
- UniProt
- P40259
- Pathways
- BCR Signaling
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