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NOC4L Antikörper

This anti-NOC4L antibody (ABIN7127072) is a Mouse Monoclonal antibody detecting NOC4L in FACS, IF. Suitable for Human.
Produktnummer ABIN7127072

Quick Overview for NOC4L Antikörper (ABIN7127072)

Target

NOC4L (Nucleolar Complex Associated 4 Homolog (NOC4L))

Reaktivität

  • 12
  • 5
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
Human

Wirt

  • 11
  • 1
Maus

Klonalität

  • 12
Monoklonal

Konjugat

  • 12
Dieser NOC4L Antikörper ist unkonjugiert

Applikation

  • 12
  • 5
  • 4
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS), Immunofluorescence (IF)
  • Spezifität

    Treg activation is critical for maintaining self-tolerance, but the translational control of this process is still poorly understood. Zhu et al. report a conserved ribosome biogenesis factor, Noc4L, that regulates mRNAs related to Treg and Tconv activation but does not affect global protein translation. Noc4L regulates translation of mRNAs related to Treg activation. Noc4L plays critical roles in activation of Tregs and Tconvs. Noc4L-mediated ribosome biogenesis is critical in controlling the activation of Tregs and maintaining immune tolerance. [Zhu et al., 2019, Cell Reports 27, 1205 1220.]

    Kreuzreaktivität (Details)

    Human

    Aufreinigung

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    Immunogen

    Recombinant full-length human NOC4L protein

    Isotyp

    IgG1
  • Applikationshinweise

    Known_Application: Flow Cytometry (1-2 μg/million cells), ,Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

    Positive_Control: HeLa or 293T cells.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    1.0 mg/mL

    Buffer

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    Konservierungsmittel

    Azide free

    Lagerung

    -20 °C,-80 °C

    Informationen zur Lagerung

    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    Haltbarkeit

    24 months
  • Target

    NOC4L (Nucleolar Complex Associated 4 Homolog (NOC4L))

    Andere Bezeichnung

    NOC4L

    Hintergrund

    NOC4 protein homolog, NOC4-like protein, Nucleolar complex protein 4 homolog, Nucleolar complex-associated protein 4-like protein,Nucleolar complex-associated protein 4-like protein (NOC4L)
    Cellular localisation: Nucleus.

    Molekulargewicht

    58.4kDa

    Gen-ID

    79050, 558536

    UniProt

    Q9BVI4
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