Rekombinanter VLDLR Antikörper (C-Term)

Produktnummer ABIN7127054

Der Maus Monoklonal anti-VLDLR Antikörper (Klon rVLDLR-1337) (ABIN7127054) detektiert spezifisch VLDLR in IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Ratte.

Kurzübersicht für Rekombinanter VLDLR Antikörper (C-Term) (ABIN7127054)

Target: VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser VLDLR Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: RVLDLR-1337

Produktdetails anti-VLDLR Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Recombinant VLDL-Receptor (Very Low Density Lipoprotein Receptor) Antibody

Spezifität: VLDLR (very low density lipoprotein receptor) is a member of the LDL receptor gene family, which includes LDL receptor, LRP, megalin, VLDLR and ApoER2. The LDL receptor family is characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain. VLDLR associates with RAP (receptor associated protein) during receptor folding, and RAP facilitates the secretion of the extracellular region of VLDLR. VLDLR is thought to mediate the interaction of extracellular Reelin and cytosolic mDab1 (mammalian disabled protein), which activates a tyrosine kinase. This pathway regulates the migration of neurons along the radial glial fiber network during brain development.

Kreuzreaktivität (Details): Human and Rat.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant human VLDLR fragment from c-terminal

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise:

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Positive_Control: HeLa or U-251 cells. Human pancreas, cerebellum, heart or skeletal muscle.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu VLDLR

Target: VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))

Andere Bezeichnung: VLDLR

Hintergrund:

Very low-density lipoprotein receptor, VLDL receptor, VLDL-R, VLDLR

Cerebellum, Heart or Skeletal Muscle., HeLaor U-251 cells.Human pancreas

Molekulargewicht: 143-161kDa

Gen-ID: 7436, 370422

UniProt: P98155

Pathways: Cellular Response to Molecule of Bacterial Origin