Inhibin alpha Antikörper (AA 73-96)

Produktnummer ABIN7126590

Der Maus Monoklonal anti-Inhibin alpha Antikörper wird verwendet zum Nachweis von Inhibin alpha in Proben von Human. Er wurde validiert für IHC.

Kurzübersicht für Inhibin alpha Antikörper (AA 73-96) (ABIN7126590)

Target: Inhibin alpha (INHA) (Inhibin, alpha (INHA))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Inhibin alpha Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: INHA-4265

Produktdetails anti-Inhibin alpha Antikörper

Bindungsspezifität: AA 73-96

Verwendungszweck: Inhibin, alpha (INHA) (Gonadal Cell Marker) Antibody

Spezifität: It recognizes a 47 kDa protein, which is identified as alpha sub-unit of Inhibin. It is a gonadal protein that preferentially suppresses the secretion of pituitary follicle-stimulating hormone (FSH). Inhibin comprises two subunits, Inhibin A and Inhibin B. Each subunit consists of the same °™ subunit, covalently linked to 1 of 2 distinct subunits, æ-°™ or æ- æ. Originally isolated from ovarian follicular fluid and characterized as a disulphide-linked dimeric glycoprotein, inhibin belongs to the transforming growth factor æ (TFG æ) superfamily. Antibodies against Inhibin are useful in making a differentiation between adrenal cortical tumors and renal cell carcinoma. Sex cord stromal tumors of the ovary as well as trophoblastic tumors also demonstrate cytoplasmic positivity. Inhibin antibody is also used to make the differential diagnosis of intra-uterine vs. ectopic pregnancy in endometrial curetting.

Kreuzreaktivität (Details): Human.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: A synthetic peptide (around aa 73-96) of α-subunit of human inhibin A protein (exact sequence is proprietary)

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise:

Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

Positive_Control: Human prostate or testis.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu Inhibin alpha

Target: Inhibin alpha (INHA) (Inhibin, alpha (INHA))

Andere Bezeichnung: INHA

Hintergrund:

A inhibin subunit, IHA, inhA, Inhibin alpha chain, Inhibin alpha subunit

Human prostate or testis.

Molekulargewicht: 47kDa

Gen-ID: 3623, 407506

UniProt: P05111

Pathways: Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion