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GCLM Antikörper

Dieser Maus Monoklonal Antikörper erkennt spezifisch GCLM in WB und IHC (f). Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN7126478

Kurzübersicht für GCLM Antikörper (ABIN7126478)

Target

Alle GCLM Antikörper anzeigen
GCLM (Glutamate-Cysteine Ligase, Modifier Subunit (GCLM))

Reaktivität

  • 80
  • 53
  • 46
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
Human

Wirt

  • 75
  • 6
Maus

Klonalität

  • 47
  • 34
Monoklonal

Konjugat

  • 34
  • 6
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
Dieser GCLM Antikörper ist unkonjugiert

Applikation

  • 56
  • 42
  • 35
  • 27
  • 24
  • 23
  • 16
  • 8
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
  • Spezifität

    GCLM known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia.

    Kreuzreaktivität (Details)

    Human.

    Aufreinigung

    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

    Immunogen

    Recombinant human full-length GCLM protein

    Isotyp

    IgG2a
  • Applikationshinweise

    Known_Application: Western Blot (1-2 μg/mL), ,Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Positive_Control: A549, HepG2 or HeLa cell lysates. Human muscle and liver tissue.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    1.0 mg/mL

    Buffer

    Prepared in 10 mM PBS, WITHOUT BSA and Azide.

    Konservierungsmittel

    Azide free

    Lagerung

    -20 °C,-80 °C

    Informationen zur Lagerung

    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

    Haltbarkeit

    24 months
  • Target

    GCLM (Glutamate-Cysteine Ligase, Modifier Subunit (GCLM))

    Andere Bezeichnung

    GCLM

    Hintergrund

    GCLM Antibody, Gamma-ECS regulatory subunit Antibody, GLCLR Antibody, GCS light chain Antibody, GSC light chain Antibody,Glutamate-Cysteine Ligase Regulatory Subunit
    Cellular localisation: Cytoplasm.

    Molekulargewicht

    31kDa

    Gen-ID

    2730, 315562

    UniProt

    P48507
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