Endoglin Antikörper (AA 74-251)

Produktnummer ABIN7126333

Der Maus Monoklonal anti-Endoglin Antikörper (Klon ENG-1326) (ABIN7126333) detektiert spezifisch Endoglin in WB, FACS und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Endoglin Antikörper (AA 74-251) (ABIN7126333)

Target: Endoglin (ENG)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Endoglin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)

Klon: ENG-1326

Produktdetails anti-Endoglin Antikörper

Bindungsspezifität: AA 74-251

Verwendungszweck: Endoglin / CD105 (Angiogenesis Marker) Antibody

Spezifität: CD105/Endoglin is a Type I membrane glycoprotein located on cell surfaces and is part of the TGF-beta receptor complex. This protein has been found on endothelial cells, activated macrophages, fibroblasts, and smooth-muscle cells. Endoglin has a role in the development of the cardiovascular system and in vascular remodeling. Its expression is regulated during heart development. CD105 is highly expressed in endothelial cells during tumor angiogenesis and inflammation, with weak or negative expression in vascular endothelium of normal tissues. Angiogenesis is a promising prognostic marker in a variety of tumors. Endoglin is a more specific and sensitive marker for tumor angiogenesis than CD31 or CD34, as it labels only newly-formed blood vessels and may serve as a prognostic marker for Prostate Adenocarcinoma, and cancers of the lung, stomach, breast, and brain.

Kreuzreaktivität (Details): Human.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant human Endoglin protein fragment (aa74-251)

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise:

Known_Application: Flow Cytometry (0.5-1 μg/million cells in 0.1ml), ,Immunofluorescence (1-2 μg/mL), ,Western Blot (1-2 μg/mL for 60 minutes at RT),Optimal dilution for a specific application should be determined.

Positive_Control: HeLa, A431 and HL-60 cells.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu Endoglin

Target: Endoglin (ENG)

Andere Bezeichnung: ENG

Hintergrund:

CD105, END, Endoglin, Eng, HHT1, S-endoglin

A431 and HL-60 cells., HeLa

Molekulargewicht: 84kDa

Gen-ID: 2022, 76753

UniProt: P17813