GLIS3 Antikörper
Kurzübersicht für GLIS3 Antikörper (ABIN7126297)
Target
Alle GLIS3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Spezifität
- GLIS3 is a member of the GLI similar zinc finger protein family, and encodes a nuclear protein with five C2H2 type zinc finger domains. It functions as both an activator and repressor of transcription, and is specifically involved in the development of pancreatic beta cells, thyroid, eye, liver and kidney. Mutations in this gene have been associated with neonatal diabetes and congenital hypothyroidism (NDH). Alternatively spliced variants that encode different protein isoforms have been described but the full length nature of only two have been determined.
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Kreuzreaktivität (Details)
- Human.
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Aufreinigung
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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Immunogen
- Recombinant full-length human GLIS3 protein
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Isotyp
- IgG1
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Applikationshinweise
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Known_Application: ELISA (For coating, order antibody without BSA), ,Flow Cytometry (1-2 μg/million cells), ,Immunoprecipitation (1-2 μg per 100-500 μg of total protein (1 mL of cell lysate)), ,Optimal dilution for a specific application should be determined.
Positive_Control: A549 or U-2 OS cells.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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Konservierungsmittel
- Azide free
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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Haltbarkeit
- 24 months
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- GLIS3 (GLIS Family Zinc Finger 3 (GLIS3))
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Andere Bezeichnung
- GLIS3
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Hintergrund
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FLJ38999, FLJ90578, GLI similar 3, GLI SIMILAR PROTEIN 3, GLIS family zinc finger 3, MGC33662, OK/KNS-cl.4, Zinc finger protein 515, Zinc finger protein GLIS3, ZNF515,GLIS family zinc finger 3 (GLIS3) / ZNF515
Cellular localisation: Nucleus. -
Molekulargewicht
- 84kDa
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Gen-ID
- 169792, 162125
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UniProt
- Q8NEA6
Target
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