GLIS3 Antikörper (N-Term)

Produktnummer ABIN2778522

Der Kaninchen Polyklonal anti-GLIS3 Antikörper wird verwendet zum Nachweis von GLIS3 in Proben von Human, Maus, Ratte, Hund, Meerschweinchen, Pferd und Kaninchen. Er wurde validiert für WB und IHC.

Kurzübersicht für GLIS3 Antikörper (N-Term) (ABIN2778522)

Target: GLIS3 (GLIS Family Zinc Finger 3 (GLIS3))

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GLIS3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-GLIS3 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: GLIS3 Antibody - N-terminal region

Sequenz: PPASQVSTAC NQISPSLQRA MNAANLNIPP SDTRSLISRE SLASTTLSLT

Homologie: Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against GLIS3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GLIS3

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8101516

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu GLIS3

Target: GLIS3 (GLIS Family Zinc Finger 3 (GLIS3))

Andere Bezeichnung: GLIS3

Hintergrund:

Background Information: GLIS3 is a member of the GLI-similar zinc finger protein family and has five C2H2-type zinc finger domains. GLIS3 functions as both a repressor and activator of transcription and is specifically involved in the development of pancreatic beta cells, the thyroid, eye, liver and kidney. Mutations in this gene have been associated with neonatal diabetes and congenital hypothyroidism (NDH).

Gene Name: GLIS family zinc finger 3

Alternative Symbols: NDH, ZNF515

Protein Name: Zinc finger protein GLIS3

Molekulargewicht: 84kDa

Gen-ID: 169792

NCBI Accession: NP_689842

UniProt: Q8NEA6