PFKFB2 Antikörper (AA 51-150) (Biotin)

Produktnummer ABIN708253

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PFKFB2 in WB, ELISA, IHC (p) und IHC (fro). Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für PFKFB2 Antikörper (AA 51-150) (Biotin) (ABIN708253)

Target: PFKFB2 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PFKFB2 Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-PFKFB2 Antikörper (Biotin)

Bindungsspezifität: AA 51-150

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Dog,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PFKFB2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu PFKFB2

Target: PFKFB2 (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2))

Andere Bezeichnung: PFKFB2

Hintergrund:

Synonyms: 6 phosphofructo 2 kinase/fructose 2 6 biphosphatase 2, 6-bisphosphatase, 6-P2ase 2, 6-P2ASE heart-type isozyme, 6PF 2 K/Fru 2 6 P2ASE heart type isozyme, 6PF-2-K/Fru-2, F262_HUMAN, Fructose 2 6 bisphosphatase cardiac isozyme, Fructose-2, PFK 2/FBPase 2, PFK/FBPase 2, PFKFB cardiac, PFKFB2.

Background: PFKFB2 is involved in both the synthesis and degradation of fructose-2,6-bisphosphate, a regulatory molecule that controls glycolysis in eukaryotes. It has a 6-phosphofructo-2-kinase activity that catalyzes the synthesis of fructose-2,6-bisphosphate, and a fructose-2,6-biphosphatase activity that catalyzes the degradation of fructose-2,6-bisphosphate. PFKFB2 regulates fructose-2,6-bisphosphate levels in the heart, while a related enzyme encoded by a different gene regulates fructose-2,6-bisphosphate levels in the liver and muscle. This enzyme functions as a homodimer. There are two named isoforms.

Gen-ID: 5208

Pathways: PI3K-Akt Signalweg, Positive Regulation of Peptide Hormone Secretion, Regulation of Carbohydrate Metabolic Process