YTHDC2 Antikörper (AA 1131-1430)
Kurzübersicht für YTHDC2 Antikörper (AA 1131-1430) (ABIN7120902)
Target
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1131-1430
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Verwendungszweck
- YTHDC2 antibody
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Aufreinigung
- Immunogen affinity purified
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
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Immunogen sequence: 1131-1430aa
Immunogen: 3'-5' RNA helicase YTHDC2
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500-1:2000, IF: 1:50-1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- YTHDC2 (YTH Domain Containing 2 (YTHDC2))
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Andere Bezeichnung
- YTHDC2
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Hintergrund
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Synonyms: 3'-5' RNA helicase YTHDC2|YTH domain-containing protein 2 (hYTHDC2)|YTHDC2
Background: This gene encodes a member of the DEAH (Asp-Glu-Ala-His) subfamily of proteins, part of the DEAD (Asp-Glu-Ala-Asp) box family of RNA helicases. The encoded protein binds to N6-methyladenosine, a common modified RNA nucleotide that is enriched in the stop codons and 3' UTRs of eukaryotic messenger RNAs. Binding of proteins to this modified nucleotide may regulate mRNA translation and stability. This gene may be associated with susceptibility to pancreatic cancer in human patients, and knockdown of this gene resulted in reduced proliferation in a human liver cancer cell line.
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Molekulargewicht
- 160 kDa
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Gen-ID
- 64848
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UniProt
- Q9H6S0
Target
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