YTHDC2 Antikörper (AA 1131-1430)

Produktnummer ABIN7271425

Produktdetails anti-YTHDC2 Antikörper

Target: YTHDC2 (YTH Domain Containing 2 (YTHDC2))

Bindungsspezifität: AA 1131-1430

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser YTHDC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: YTHDC2 Rabbit pAb

Sequenz: HSLFLRRMRA PSKPWSQVDE ATIRAIIAVL STEEQSAGLQ QPSGIGQRPR PMSSEELPLA SSWRSNNSRK SSADTEFSDE CTTAERVLMK SPSPALHPPQ KYKDRGILHP KRGTEDRSDQ SSLKSTDSSS YPSPCASPSP PSSGKGSKSP SPRPNMPVRY FIMKSSNLRN LEISQQKGIW STTPSNERKL NRAFWESSIV YLVFSVQGSG HFQGFSRMSS EIGREKSQDW GSAGLGGVFK VEWIRKESLP FQFAHHLLNP WNDNKKVQIS RDGQELEPLV GEQLLQLWER LPLGEKNTTD

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1131-1430 of human YTHDC2 (NP_073739.3).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu YTHDC2

Target: YTHDC2 (YTH Domain Containing 2 (YTHDC2))

Andere Bezeichnung: YTHDC2 (YTHDC2 Produkte)

Synonyme: 3010002F02Rik antikoerper, BC037178 antikoerper, CAHL antikoerper, YTH domain containing 2 antikoerper, Ythdc2 antikoerper, YTHDC2 antikoerper

Hintergrund: This gene encodes a member of the DEAH (Asp-Glu-Ala-His) subfamily of proteins, part of the DEAD (Asp-Glu-Ala-Asp) box family of RNA helicases. The encoded protein binds to N6-methyladenosine, a common modified RNA nucleotide that is enriched in the stop codons and 3' UTRs of eukaryotic messenger RNAs. Binding of proteins to this modified nucleotide may regulate mRNA translation and stability. This gene may be associated with susceptibility to pancreatic cancer in human patients, and knockdown of this gene resulted in reduced proliferation in a human liver cancer cell line. [provided by RefSeq, Sep 2016],YTHDC2;CAHL,Epigenetics & Nuclear Signaling,RNA Binding,Cell Biology & Developmental Biology,YTHDC2

Molekulargewicht: 160kDa

Gen-ID: 64848

UniProt: Q9H6S0