Vinculin Antikörper
Kurzübersicht für Vinculin Antikörper (ABIN7120772)
Target
Alle Vinculin (VCL) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- VCL antibody
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Aufreinigung
- Protein A+G purification
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- vinculin
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Isotyp
- IgG1
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Applikationshinweise
- WB: 1:2000-1:20000, IHC: 1:50-1:500, IF: 1:50-1:500
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- Vinculin (VCL)
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Andere Bezeichnung
- VCL
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Hintergrund
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Synonyms: Vinculin|Metavinculin (MV)|VCL
Background: Vinculin belongs to the vinculin/alpha-catenin family. It is an actin filament(F-actin)-binding protein which involved in cell-matrix adhesion and cell-cell adhesion. Vinculin regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. It may also play important roles in cell morphology and locomotion. Vinculin is a 117- kDa, 1,066-amino-acid protein which is ubiquitously expressed. Its splice variant, metavinculin(124 kDa), is muscle-specific.
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Molekulargewicht
- 124 kDa
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UniProt
- P18206
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Pathways
- Cell-Cell Junction Organization, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2
Target
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