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GALE Antikörper

GALE Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7120594
  • Target Alle GALE Antikörper anzeigen
    GALE (UDP-Galactose-4-Epimerase (GALE))
    Reaktivität
    • 33
    • 17
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 43
    • 4
    Kaninchen
    Klonalität
    • 45
    • 2
    Polyklonal
    Konjugat
    • 19
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GALE Antikörper ist unkonjugiert
    Applikation
    • 37
    • 15
    • 12
    • 12
    • 5
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    Aufreinigung
    Immunogen affinity purified
    Reinheit
    ≥95 % as determined by SDS-PAGE
    Immunogen
    UDP-galactose-4-epimerase
    Isotyp
    IgG
    Top Product
    Discover our top product GALE Primärantikörper
  • Applikationshinweise
    WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:10 - 1:100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3 ,
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Haltbarkeit
    12 months
  • Target
    GALE (UDP-Galactose-4-Epimerase (GALE))
    Andere Bezeichnung
    GALE (GALE Produkte)
    Hintergrund
    Synonyms: Background:This gene encodes UDP-galactose-4-epimerase which catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose, but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids. Mutations in this gene result in epimerase-deficiency galactosemia, also referred to as galactosemia type 3, a disease characterized by liver damage, early-onset cataracts, deafness and mental retardation, with symptoms ranging from mild ('peripheral' form) to severe ('generalized' form). Multiple alternatively spliced transcripts encoding the same protein have been identified.
    Molekulargewicht
    36 kDa
    Gen-ID
    2582
    UniProt
    Q14376
    Pathways
    Response to Water Deprivation, Cellular Glucan Metabolic Process
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