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GALE Antikörper

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch GALE in WB, ELISA, IHC und IF. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.
Produktnummer ABIN7120594

Kurzübersicht für GALE Antikörper (ABIN7120594)

Target

Alle GALE Antikörper anzeigen
GALE (UDP-Galactose-4-Epimerase (GALE))

Reaktivität

  • 36
  • 18
  • 5
  • 5
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 47
  • 4
Kaninchen

Klonalität

  • 49
  • 2
Polyklonal

Konjugat

  • 22
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser GALE Antikörper ist unkonjugiert

Applikation

  • 41
  • 16
  • 13
  • 13
  • 6
  • 5
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • Aufreinigung

    Immunogen affinity purified

    Reinheit

    ≥95 % as determined by SDS-PAGE

    Immunogen

    UDP-galactose-4-epimerase

    Isotyp

    IgG
  • Applikationshinweise

    WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:10 - 1:100

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3 ,

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    Haltbarkeit

    12 months
  • Target

    GALE (UDP-Galactose-4-Epimerase (GALE))

    Andere Bezeichnung

    GALE

    Hintergrund

    Synonyms: Background:This gene encodes UDP-galactose-4-epimerase which catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. The bifunctional nature of the enzyme has the important metabolic consequence that mutant cells (or individuals) are dependent not only on exogenous galactose, but also on exogenous N-acetylgalactosamine as a necessary precursor for the synthesis of glycoproteins and glycolipids. Mutations in this gene result in epimerase-deficiency galactosemia, also referred to as galactosemia type 3, a disease characterized by liver damage, early-onset cataracts, deafness and mental retardation, with symptoms ranging from mild ('peripheral' form) to severe ('generalized' form). Multiple alternatively spliced transcripts encoding the same protein have been identified.

    Molekulargewicht

    36 kDa

    Gen-ID

    2582

    UniProt

    Q14376

    Pathways

    Response to Water Deprivation, Cellular Glucan Metabolic Process
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