UBE2C Antikörper
Kurzübersicht für UBE2C Antikörper (ABIN7120541)
Target
Alle UBE2C Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- UBE2C antibody
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Aufreinigung
- Protein A+G purification
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Reinheit
- ≥95 % as determined by SDS-PAGE
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Immunogen
- ubiquitin-conjugating enzyme E2C
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Isotyp
- IgG1
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Applikationshinweise
- WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:10-1:100
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- UBE2C (Ubiquitin-Conjugating Enzyme E2C (UBE2C))
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Andere Bezeichnung
- UBE2C
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Hintergrund
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Synonyms: Ubiquitin-conjugating enzyme E2 C|(E3-independent) E2 ubiquitin-conjugating enzyme C|E2 ubiquitin-conjugating enzyme C|UbcH10|Ubiquitin carrier protein C|Ubiquitin-protein ligase C|UBE2C|UBCH10
Background: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'-and 'Lys-48'-linked polyubiquitination. Acts as an essential factor of the anaphase promoting complex/cyclosome(APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Acts by initiating 'Lys-11'-linked polyubiquitin chains on APC/C substrates, leading to the degradation of APC/C substrates by the proteasome and promoting mitotic exit.
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Molekulargewicht
- 17 kDa
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Gen-ID
- 11065
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UniProt
- O00762
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Pathways
- Ubiquitin Proteasome Pathway
Target
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