USP9X Antikörper

Produktnummer ABIN7120533

Dieses Anti-USP9X-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von USP9X in WB, ELISA, IHC, IF und IP. Geeignet für Human, Maus und Ratte.

Kurzübersicht für USP9X Antikörper (ABIN7120533)

Target: USP9X (Ubiquitin Specific Peptidase 9, X-Linked (USP9X))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser USP9X Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Produktdetails anti-USP9X Antikörper

Verwendungszweck: USP9X antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: ubiquitin specific peptidase 9, X-linked

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:5000, IF: 1:10-1:100, IHC: 1:20-1:200, IP: 1:200-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu USP9X

Target: USP9X (Ubiquitin Specific Peptidase 9, X-Linked (USP9X))

Andere Bezeichnung: USP9X

Hintergrund:

Synonyms: Probable ubiquitin carboxyl-terminal hydrolase FAF-X|Deubiquitinating enzyme FAF-X|Fat facets in mammals (hFAM)|Fat facets protein-related, X-linked|Ubiquitin thioesterase FAF-X|Ubiquitin-specific protease 9, X chromosome|Ubiquitin-specific-processing protease FAF-X|USP9X|DFFRX|FAM|USP9

Background: Deubiquitinase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. May therefore play an important regulatory role at the level of protein turnover by preventing degradation of proteins through the removal of conjugated ubiquitin. Essential component of TGF-beta/BMP signaling cascade. Regulates chromosome alignment and segregation in mitosis by regulating the localization of BIRC5/survivin to mitotic centromeres. Specifically hydrolyzes both 'Lys-29'-and 'Lys-33'-linked polyubiquitins chains. Specifically deubiquitinates monoubiquitinated SMAD4, opposing the activity of E3 ubiquitin-protein ligase TRIM33. Involved in axonal growth and neuronal cell migration.

Molekulargewicht: 260-290 kDa

Gen-ID: 8239

UniProt: Q93008