U2AF1 Antikörper

Produktnummer ABIN7120448

Der Maus Monoklonal Anti-U2AF1-Antikörper wurde für WB, IHC, ELISA und IP validiert. Er ist geeignet, U2AF1 in Proben von Human zu detektieren.

Kurzübersicht für U2AF1 Antikörper (ABIN7120448)

Target: U2AF1 (U2 Small Nuclear RNA Auxiliary Factor 1 (U2AF1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser U2AF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)

Klon: 1E9

Produktdetails anti-U2AF1 Antikörper

Verwendungszweck: U2AF1 antibody

Aufreinigung: Protein A+G purification

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: U2 small nuclear RNA auxiliary factor 1

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:5000, IHC: 1:20-1:200, IP: 1:200-1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu U2AF1

Target: U2AF1 (U2 Small Nuclear RNA Auxiliary Factor 1 (U2AF1))

Andere Bezeichnung: U2AF1

Hintergrund:

Synonyms: Splicing factor U2AF 35 kDa subunit|U2 auxiliary factor 35 kDa subunit|U2 small nuclear RNA auxiliary factor 1|U2 snRNP auxiliary factor small subunit|U2AF1|U2AF35|U2AFBP

Background: U2 auxiliary factor(U2AF), comprising a large and a small subunit, is a non-snRNP protein required for the binding of U2 snRNP to the pre-mRNA branch site. U2(RNU2) small nuclear RNA auxiliary factor 1(U2AF1,synonyms: RN, FP793, U2AF35, U2AFBP, RNU2AF1)is the small subunit which plays a critical role in both constitutive and enhancer-dependent RNA splicing by directly mediating interactions between the large subunit and proteins bound to the enhancers. The U2AF1 gene is localized to chromosome 21q22.3, which is the critical region for three diseases, progressive myoclonus epilepsy, autoimmune polyglandular disease type 1, and one form of bipolar affective disorder.

Molekulargewicht: 38 kDa

Gen-ID: 7307

UniProt: Q01081