TNFAIP1 Antikörper

Produktnummer ABIN7120411

Dieser Maus Monoklonal Antikörper detektiert spezifisch TNFAIP1 in WB, ELISA und IHC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für TNFAIP1 Antikörper (ABIN7120411)

Target: TNFAIP1 (Tumor Necrosis Factor, alpha-Induced Protein 1 (Endothelial) (TNFAIP1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TNFAIP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Klon: 2H3

Produktdetails anti-TNFAIP1 Antikörper

Verwendungszweck: TNFAIP1 antibody

Aufreinigung: Protein A+G purification

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: tumor necrosis factor, alpha-induced protein 1(endothelial)

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB: 1:1000-1:6000, IHC: 1:50-1:600

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu TNFAIP1

Target: TNFAIP1 (Tumor Necrosis Factor, alpha-Induced Protein 1 (Endothelial) (TNFAIP1))

Andere Bezeichnung: TNFAIP1

Hintergrund:

Synonyms: BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 (hBACURD2)|BTB/POZ domain-containing protein TNFAIP1|Protein B12|Tumor necrosis factor, alpha-induced protein 1, endothelial|TNFAIP1|BACURD2|EDP1

Background: Substrate-specific adapter of a BCR(BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(BACURD2) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. Its interaction with RHOB may regulate apoptosis. May enhance the PCNA-dependent DNA polymerase delta activity.

Molekulargewicht: 36 kDa

Gen-ID: 7126

UniProt: Q13829